4Q93

Crystal structure of resveratrol bound human tyrosyl tRNA synthetase

Summary for 4Q93

Entry DOI	10.2210/pdb4q93/pdb
Related	1N3L 1Q11 4QBT
Descriptor	Tyrosine--tRNA ligase, cytoplasmic, RESVERATROL, SULFATE ION, ... (7 entities in total)
Functional Keywords	resveratrol, aminoacyl trna synthetases, amino acid activation, active site, ligase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	43347.76
Authors	Mathew, S.,Schimmel, P. (deposition date: 2014-04-28, release date: 2014-12-17, Last modification date: 2023-09-20)
Primary citation	Sajish, M.,Schimmel, P. A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol. Nature, 519:370-373, 2014 Cited by PubMed: 25533949 DOI: 10.1038/nature14028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation