4Q93
Crystal structure of resveratrol bound human tyrosyl tRNA synthetase
Summary for 4Q93
Entry DOI | 10.2210/pdb4q93/pdb |
Related | 1N3L 1Q11 4QBT |
Descriptor | Tyrosine--tRNA ligase, cytoplasmic, RESVERATROL, SULFATE ION, ... (7 entities in total) |
Functional Keywords | resveratrol, aminoacyl trna synthetases, amino acid activation, active site, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 43347.76 |
Authors | Mathew, S.,Schimmel, P. (deposition date: 2014-04-28, release date: 2014-12-17, Last modification date: 2023-09-20) |
Primary citation | Sajish, M.,Schimmel, P. A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol. Nature, 519:370-373, 2014 Cited by PubMed: 25533949DOI: 10.1038/nature14028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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