4Q74

F241A Fc

Summary for 4Q74

• Entry DOI: 10.2210/pdb4q74/pdb
• Related: 4Q6Y 4Q7D
• Descriptor: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P01857
• Total number of polymer chains: 2
• Total formula weight: 54469.94

Authors

Ahmed, A.A.,Giddens, J.,Pincetic, A.,Lomino, J.V.,Ravetch, J.V.,Wang, L.X.,Bjorkman, P.J. (deposition date: 2014-04-24, release date: 2014-07-23, Last modification date: 2023-09-20)

• Primary citation: Ahmed, A.A.,Giddens, J.,Pincetic, A.,Lomino, J.V.,Ravetch, J.V.,Wang, L.X.,Bjorkman, P.J.; Structural characterization of anti-inflammatory immunoglobulin g fc proteins.; J.Mol.Biol., 426:3166-3179, 2014; PubMed: 25036289; DOI: 10.1016/j.jmb.2014.07.006

Experimental method

X-RAY DIFFRACTION (2.19 Å)