4PZF

Berberine bridge enzyme G164A variant, a reticuline dehydrogenase

Summary for 4PZF

Entry DOI	10.2210/pdb4pzf/pdb
Related	3D2H 4PVE 4PVH 4PVJ 4PVK 4PWB 4PWC
Descriptor	Reticuline oxidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... (7 entities in total)
Functional Keywords	flavoprotein, bi-covalent flavinylation, oxidoreductase, reticuline oxidase, berberine bridge-forming enzyme, tetrahydroprotoberberine synthase
Biological source	Eschscholzia californica (California poppy)
Cellular location	Cytoplasmic vesicle: P30986
Total number of polymer chains	4
Total formula weight	247542.27
Authors	Zafred, D.,Wallner, S.,Steiner, B.,Macheroux, P. (deposition date: 2014-03-30, release date: 2014-04-23, Last modification date: 2023-09-20)
Primary citation	Zafred, D.,Steiner, B.,Teufelberger, A.R.,Hromic, A.,Karplus, P.A.,Schofield, C.J.,Wallner, S.,Macheroux, P. Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282:3060-3074, 2015 Cited by PubMed: 25619330 DOI: 10.1111/febs.13212 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation