4PF6

CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM ROSEOBACTER DENITRIFICANS (RD1_0742, TARGET EFI-510239) WITH BOUND 3-DEOXY-D-MANNO-OCT-2-ULOSONIC ACID (KDO)

Summary for 4PF6

• Entry DOI: 10.2210/pdb4pf6/pdb
• Related: 4PF8
• Descriptor: C4-dicarboxylate-binding protein, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, TRIETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: trap periplasmic solute binding family, enzyme function initiative, efi, structural genomics, transport protein
• Biological source: Roseobacter denitrificans (Erythrobacter sp. (strain OCh 114))
• Total number of polymer chains: 1
• Total formula weight: 37251.82

Authors

Vetting, M.W.,Al Obaidi, N.F.,Morisco, L.L.,Wasserman, S.R.,Stead, M.,Attonito, J.D.,Scott Glenn, A.,Chowdhury, S.,Evans, B.,Hillerich, B.,Love, J.,Seidel, R.D.,Whalen, K.L.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2014-04-28, release date: 2014-05-14, Last modification date: 2023-12-27)

• Primary citation: Vetting, M.W.,Al-Obaidi, N.,Zhao, S.,San Francisco, B.,Kim, J.,Wichelecki, D.J.,Bouvier, J.T.,Solbiati, J.O.,Vu, H.,Zhang, X.,Rodionov, D.A.,Love, J.D.,Hillerich, B.S.,Seidel, R.D.,Quinn, R.J.,Osterman, A.L.,Cronan, J.E.,Jacobson, M.P.,Gerlt, J.A.,Almo, S.C.; Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.; Biochemistry, 54:909-931, 2015; PubMed: 25540822; DOI: 10.1021/bi501388y

Experimental method

X-RAY DIFFRACTION (1.75 Å)