4P3R
Cryogenic WT DHFR, time-averaged ensemble
Summary for 4P3R
Entry DOI | 10.2210/pdb4p3r/pdb |
Related | 4KJK 4P3R |
Descriptor | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | rossmann fold, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 19204.14 |
Authors | Keedy, D.A.,van den Bedem, H.,Fraser, J.S. (deposition date: 2014-03-10, release date: 2014-05-14, Last modification date: 2023-12-27) |
Primary citation | Keedy, D.A.,van den Bedem, H.,Sivak, D.A.,Petsko, G.A.,Ringe, D.,Wilson, M.A.,Fraser, J.S. Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR. Structure, 22:899-910, 2014 Cited by PubMed: 24882744DOI: 10.1016/j.str.2014.04.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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