4OYD
Crystal structure of a computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein
Summary for 4OYD
Entry DOI | 10.2210/pdb4oyd/pdb |
Descriptor | Apoptosis regulator BHRF1, Computationally designed Inhibitor, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, apoptosis, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Epstein-Barr virus (HHV-4) More |
Cellular location | Host membrane ; Single-pass membrane protein : P0C6Z1 |
Total number of polymer chains | 4 |
Total formula weight | 64059.13 |
Authors | Shen, B.,Procko, E.,Baker, D.,Stoddard, B. (deposition date: 2014-02-11, release date: 2014-07-09, Last modification date: 2023-12-27) |
Primary citation | Procko, E.,Berguig, G.Y.,Shen, B.W.,Song, Y.,Frayo, S.,Convertine, A.J.,Margineantu, D.,Booth, G.,Correia, B.E.,Cheng, Y.,Schief, W.R.,Hockenbery, D.M.,Press, O.W.,Stoddard, B.L.,Stayton, P.S.,Baker, D. A computationally designed inhibitor of an epstein-barr viral bcl-2 protein induces apoptosis in infected cells. Cell, 157:1644-1656, 2014 Cited by PubMed: 24949974DOI: 10.1016/j.cell.2014.04.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report