4OYD
Crystal structure of a computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Apoptosis regulator BHRF1 | polymer | 158 | 18118.5 | 2 | UniProt (P0C6Z1) Pfam (PF00452) | Epstein-Barr virus (HHV-4) | Early antigen protein R,EA-R,Nuclear antigen |
| 2 | B, D (B, D) | Computationally designed Inhibitor | polymer | 117 | 13880.1 | 2 | synthetic construct | ||
| 3 | E (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A, C: 2 - 158 (UniProt: P0C6Z1)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 63997.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 62.1 | |
| All* | Total formula weight | 64059.1 |
