4OQM
Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU
Summary for 4OQM
Entry DOI | 10.2210/pdb4oqm/pdb |
Related | 4OQL 4OQN 4OQX |
Descriptor | Thymidine kinase, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidine-2,4(1H,3H)-dione, SULFATE ION, ... (4 entities in total) |
Functional Keywords | dna synthesis, thymidine kinase, atp-binding, nucleotide-binding, transferase, 5-ethynyluridine nucleoside derivative |
Biological source | Human herpesvirus 1 (HHV-1) |
Total number of polymer chains | 2 |
Total formula weight | 72933.34 |
Authors | Pernot, L.,Neef, A.B.,Westermaier, Y.,Perozzo, R.,Luedtke, N.,Scapozza, L. (deposition date: 2014-02-10, release date: 2014-08-13, Last modification date: 2023-09-20) |
Primary citation | Pernot, L.,Neef, A.B.,Westermaier, Y.,Perozzo, R.,Luedtke, N.,Scapozza, L. Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU To be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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