4OQ4

Crystal Structure of E18A Human DJ-1

Summary for 4OQ4

Entry DOI	10.2210/pdb4oq4/pdb
Related	1SOA 3CY6 3CYF 3CZA
Descriptor	Protein DJ-1, SODIUM ION (3 entities in total)
Functional Keywords	cysteine-sulfinic acid, chaperone
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor: Q99497
Total number of polymer chains	1
Total formula weight	20196.28
Authors	Prahlad, J.,Hauser, D.N.,Milkovic, N.M.,Cookson, M.R.,Wilson, M.A. (deposition date: 2014-02-07, release date: 2014-02-19, Last modification date: 2023-09-20)
Primary citation	Prahlad, J.,Hauser, D.N.,Milkovic, N.M.,Cookson, M.R.,Wilson, M.A. Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers. J Neurochem, 130:839-853, 2014 Cited by PubMed: 24832775 DOI: 10.1111/jnc.12763 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.49 Å)

Structure validation