4OME

X-ray structure of human glutamate carboxypeptidase II in complex with DCCBL, a urea based inhibitor with distal carborane moiety

Summary for 4OME

• Entry DOI: 10.2210/pdb4ome/pdb
• Descriptor: Glutamate carboxypeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: hydrolase, metallopeptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane ; Single-pass type II membrane protein . Isoform PSMA': Cytoplasm: Q04609
• Total number of polymer chains: 1
• Total formula weight: 83158.28

Authors

Barinka, C.,Ptacek, J.,Novakova, Z.,Byun, Y. (deposition date: 2014-01-27, release date: 2015-02-18, Last modification date: 2020-07-29)

• Primary citation: Barinka, C.,Ptacek, J.,Novakova, Z.,Byun, Y.; X-ray structure of human glutamate carboxypeptidase II in complex with DCCBL, a urea based inhibitor with distal carborane moiety; To be Published,

Experimental method

X-RAY DIFFRACTION (1.79 Å)