4OLG
Crystal structure of AmpC beta-lactamase in complex with covalently bound N-formyl 7-aminocephalosporanic acid
Summary for 4OLG
Entry DOI | 10.2210/pdb4olg/pdb |
Related | 1kvl 1kvm |
Descriptor | Beta-lactamase, (2R,5Z)-5-[(acetyloxy)methylidene]-2-[(1R)-1-(formylamino)-2-oxoethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | ampc beta-lactamase, class, cephalosporinase, hydrolase |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 79871.39 |
Authors | Shoichet, B.K.,Barelier, S. (deposition date: 2014-01-23, release date: 2014-05-28, Last modification date: 2014-06-18) |
Primary citation | Barelier, S.,Cummings, J.A.,Rauwerdink, A.M.,Hitchcock, D.S.,Farelli, J.D.,Almo, S.C.,Raushel, F.M.,Allen, K.N.,Shoichet, B.K. Substrate deconstruction and the nonadditivity of enzyme recognition. J.Am.Chem.Soc., 136:7374-7382, 2014 Cited by PubMed: 24791931DOI: 10.1021/ja501354q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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