4OJ8

Crystal structure of carbapenem synthase in complex with (3S,5S)-carbapenam

Summary for 4OJ8

Entry DOI	10.2210/pdb4oj8/pdb
Descriptor	(5R)-carbapenem-3-carboxylate synthase, FE (II) ION, 2-OXOGLUTARIC ACID, ... (6 entities in total)
Functional Keywords	oxidoreductase, oxygenase, iron, 2-oxoglutaric acid, antibiotic biosynthesis, carbapenam
Biological source	Pectobacterium carotovorum subsp. carotovorum
Cellular location	Cytoplasm : Q9XB59
Total number of polymer chains	3
Total formula weight	102471.87
Authors	Boal, A.K.,Rosenzweig, A.C. (deposition date: 2014-01-20, release date: 2014-04-02, Last modification date: 2023-09-20)
Primary citation	Chang, W.C.,Guo, Y.,Wang, C.,Butch, S.E.,Rosenzweig, A.C.,Boal, A.K.,Krebs, C.,Bollinger, J.M. Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics. Science, 343:1140-1144, 2014 Cited by PubMed: 24604200 DOI: 10.1126/science.1248000 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation