4OCD
In and Out the minor groove: Interaction of an AT rich-DNA with the CD27 drug
Summary for 4OCD
Entry DOI | 10.2210/pdb4ocd/pdb |
Descriptor | d(AAAATTTT), N1-(4,5-dihydro-1H-imidazol-2-yl)-N4-(4-((4,5-dihydro-1H-imidazol-2-yl)amino)phenyl)benzene-1,4-diamine (3 entities in total) |
Functional Keywords | dna minor groove binding drugs, all-at dna, dicationic drug, imidazoline drug, dna |
Total number of polymer chains | 3 |
Total formula weight | 8280.14 |
Authors | Acosta-Reyes, F.J.,Dardonville, C.,de Koning, H.P.,Natto, M.,Subirana, J.A.,Campos, J.L. (deposition date: 2014-01-08, release date: 2014-06-11, Last modification date: 2024-02-28) |
Primary citation | Acosta-Reyes, F.J.,Dardonville, C.,de Koning, H.P.,Natto, M.,Subirana, J.A.,Campos, J.L. In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27 Acta Crystallogr.,Sect.D, D70:1614-1621, 2014 Cited by PubMed: 24914972DOI: 10.1107/S139900471400697X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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