4O03
Crystal structure of Ca2+ bound prothrombin deletion mutant residues 146-167
Summary for 4O03
Entry DOI | 10.2210/pdb4o03/pdb |
Related | 1NL1 4NZQ |
Descriptor | Prothrombin, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | prothrombin, kringle, serine protease, coagulation, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 64421.68 |
Authors | Pozzi, N.,Chen, Z.,Shropshire, D.B.,Pelc, L.A.,Di Cera, E. (deposition date: 2013-12-13, release date: 2014-05-21, Last modification date: 2023-12-06) |
Primary citation | Pozzi, N.,Chen, Z.,Pelc, L.A.,Shropshire, D.B.,Di Cera, E. The linker connecting the two kringles plays a key role in prothrombin activation. Proc.Natl.Acad.Sci.USA, 111:7630-7635, 2014 Cited by PubMed: 24821807DOI: 10.1073/pnas.1403779111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.38 Å) |
Structure validation
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