4NQE
Crystal structure of TCR-MR1 ternary complex bound to 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil
Summary for 4NQE
Entry DOI | 10.2210/pdb4nqe/pdb |
Related | 4NQC 4NQD |
Descriptor | Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TCR alpha, ... (6 entities in total) |
Functional Keywords | immune complex, mr1, tcr, ig-domain, protein binding, schiff base, membrane, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 187945.46 |
Authors | Birkinshaw, R.W.,Rossjohn, J. (deposition date: 2013-11-25, release date: 2014-04-16, Last modification date: 2020-02-19) |
Primary citation | Corbett, A.J.,Eckle, S.B.,Birkinshaw, R.W.,Liu, L.,Patel, O.,Mahony, J.,Chen, Z.,Reantragoon, R.,Meehan, B.,Cao, H.,Williamson, N.A.,Strugnell, R.A.,Van Sinderen, D.,Mak, J.Y.,Fairlie, D.P.,Kjer-Nielsen, L.,Rossjohn, J.,McCluskey, J. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature, 509:361-365, 2014 Cited by PubMed: 24695216DOI: 10.1038/nature13160 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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