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4NNL

Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide

Summary for 4NNL
Entry DOI10.2210/pdb4nnl/pdb
Related3SFJ 4NNM
DescriptorTax1-binding protein 3, TIP-1 PDZ domain (3 entities in total)
Functional Keywordstax-interacting protein-1, tip-1, pdz, pdz-peptide, protein binding
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: O14907
Total number of polymer chains4
Total formula weight25164.55
Authors
Amacher, J.F.,Madden, D.R. (deposition date: 2013-11-18, release date: 2015-01-21, Last modification date: 2023-09-20)
Primary citationCushing, P.R.,Amacher, J.F.,Vouilleme, L.,Culatti, S.,Deng, B.,Gerber, S.A.,Boisguerin, P.,Madden, D.R.
A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
To be Published,
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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