4NIK

Structure of human Gankyrin in complex to the single chain antibody F5

Summary for 4NIK

• Entry DOI: 10.2210/pdb4nik/pdb
• Related: 1QYM 1UOH
• Descriptor: 26S proteasome non-ATPase regulatory subunit 10, Single-chain Fv fragment antibody (3 entities in total)
• Functional Keywords: beta-hairpin-alpha-hairpin repeat, oncoprotein, 26s proteasome, oncoprotein-immune system complex, oncoprotein/immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : O75832
• Total number of polymer chains: 2
• Total formula weight: 51738.00

Authors

Sato, Y.,Weiss, E.,Rochel, N. (deposition date: 2013-11-06, release date: 2014-09-10, Last modification date: 2023-11-08)

• Primary citation: Robin, G.,Sato, Y.,Desplancq, D.,Rochel, N.,Weiss, E.,Martineau, P.; Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes; J.Mol.Biol., 426:3729-3743, 2014; PubMed: 25174334; DOI: 10.1016/j.jmb.2014.08.013

Experimental method

X-RAY DIFFRACTION (2.5 Å)