4NI7
Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025)
Summary for 4NI7
Entry DOI | 10.2210/pdb4ni7/pdb |
Descriptor | Interleukin-6, SOMAmer SL1025, SODIUM ION, ... (4 entities in total) |
Functional Keywords | interleukin-6, cytokine-dna complex, cytokine/dna |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05231 |
Total number of polymer chains | 2 |
Total formula weight | 32586.00 |
Authors | Davies, D.,Edwards, T.,Gelinas, A.,Jarvis, T.,Clifton, M.C. (deposition date: 2013-11-05, release date: 2014-01-22, Last modification date: 2023-09-20) |
Primary citation | Gelinas, A.D.,Davies, D.R.,Edwards, T.E.,Rohloff, J.C.,Carter, J.D.,Zhang, C.,Gupta, S.,Ishikawa, Y.,Hirota, M.,Nakaishi, Y.,Jarvis, T.C.,Janjic, N. Crystal structure of interleukin-6 in complex with a modified nucleic Acid ligand. J.Biol.Chem., 289:8720-8734, 2014 Cited by PubMed: 24415767DOI: 10.1074/jbc.M113.532697 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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