4NI7
Crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (SOMAMER SL1025)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-6 | polymer | 186 | 21137.2 | 1 | UniProt (P05231) Pfam (PF00489) | Homo sapiens (human) | IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2 |
| 2 | B (B) | SOMAmer SL1025 | polymer | 32 | 11402.9 | 1 | |||
| 3 | C, D (B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 0 - 184 (UniProt: P05231)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32540.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 46.0 | |
| All* | Total formula weight | 32586.0 |
