Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4N9K

crystal structure of beta-lactamse PenP_E166S in complex with cephaloridine

Summary for 4N9K
Entry DOI10.2210/pdb4n9k/pdb
Related4N92 4N9L
DescriptorBeta-lactamase, 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID (3 entities in total)
Functional Keywordshydrolase, hydrolase-antibiotic complex, hydrolase/antibiotic
Biological sourceBacillus licheniformis
Cellular locationCell membrane; Lipid-anchor (Probable): P00808
Total number of polymer chains2
Total formula weight60252.37
Authors
Pan, X.,Wong, W.,Zhao, Y. (deposition date: 2013-10-21, release date: 2014-09-10)
Primary citationPan, X.,Wong, W.,He, Y.,Jiang, Y.,Zhao, Y.
Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation
Biochemistry, 53:5414-5423, 2014
Cited by
PubMed: 25020031
DOI: 10.1021/bi401609h
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon