4MZL
Crystal Structure of MTIP from Plasmodium falciparum in complex with HBS myoA, a hydrogen bond surrogate myoA helix mimetic
Summary for 4MZL
Entry DOI | 10.2210/pdb4mzl/pdb |
Related | 4AOM 4MZJ 4MZK |
Related PRD ID | PRD_001188 |
Descriptor | Myosin A tail domain interacting protein, hydrogen bond surrogate (HBS) myoA helix mimetic (3 entities in total) |
Functional Keywords | actomyosin motor, stapled peptides, protein binding-inhibitor complex, alpha-helix mimetic, protein binding/inhibitor |
Biological source | Plasmodium falciparum 3D7 More |
Cellular location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : 4MZL |
Total number of polymer chains | 4 |
Total formula weight | 37157.59 |
Authors | Douse, C.H.,Garnett, J.A.,Maas, S.J.,Cota, E.,Tate, E.W. (deposition date: 2013-09-30, release date: 2013-11-06, Last modification date: 2023-06-07) |
Primary citation | Douse, C.H.,Maas, S.J.,Thomas, J.C.,Garnett, J.A.,Sun, Y.,Cota, E.,Tate, E.W. Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction. Acs Chem.Biol., 8:506-512, 2014 Cited by PubMed: 25084543DOI: 10.1021/cb500271c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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