4MMD
Crystal structure of LeuBAT (delta6 mutant) in complex with (S)-duloxetine
Summary for 4MMD
Entry DOI | 10.2210/pdb4mmd/pdb |
Related | 4MM4 4MM5 4MM6 4MM7 4MM8 4MM9 4MMA 4MMB 4MMC 4MME 4MMF |
Descriptor | Transporter, SODIUM ION, (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, ... (5 entities in total) |
Functional Keywords | transporter, transport protein |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 2 |
Total formula weight | 117700.68 |
Authors | Wang, H.,Gouaux, E. (deposition date: 2013-09-08, release date: 2013-10-16, Last modification date: 2024-02-28) |
Primary citation | Wang, H.,Goehring, A.,Wang, K.H.,Penmatsa, A.,Ressler, R.,Gouaux, E. Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature, 503:141-145, 2013 Cited by PubMed: 24121440DOI: 10.1038/nature12648 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report