4M1U

The crystal structure of Stx2 and a disaccharide ligand

Summary for 4M1U

Entry DOI	10.2210/pdb4m1u/pdb
Related	1BOS 1R4P
Descriptor	Shiga toxin 2 A-subunit, Shiga toxin 2 B subunit, 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-methyl beta-D-galactopyranoside, ... (5 entities in total)
Functional Keywords	rrna n-glycosylase, hydrolase
Biological source	Escherichia coli O157:H7 More
Total number of polymer chains	6
Total formula weight	73749.64
Authors	Yin, J.,James, M.N.G.,Jacobson, J.M.,Kitov, P.I.,Bundle, D.R.,Mulvey, G.,Armstrong, G. (deposition date: 2013-08-04, release date: 2013-11-20, Last modification date: 2023-09-20)
Primary citation	Jacobson, J.M.,Yin, J.,Kitov, P.I.,Mulvey, G.,Griener, T.P.,James, M.N.,Armstrong, G.,Bundle, D.R. The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor. J.Biol.Chem., 289:885-894, 2014 Cited by PubMed: 24225957 DOI: 10.1074/jbc.M113.518886 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.56 Å)

Structure validation