4LYI
Crystal Structure of apo-BRD4(1)
Summary for 4LYI
Entry DOI | 10.2210/pdb4lyi/pdb |
Related | 4LYS 4LYW 4LZR 4LZS |
Descriptor | Bromodomain-containing protein 4, 1,2-ETHANEDIOL, IODIDE ION, ... (6 entities in total) |
Functional Keywords | bromodomain, epigenetic reader protein, acetylated lysin, histone tail, nucleus, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O60885 |
Total number of polymer chains | 1 |
Total formula weight | 15948.02 |
Authors | Wohlwend, D. (deposition date: 2013-07-31, release date: 2014-01-15, Last modification date: 2024-02-28) |
Primary citation | Lucas, X.,Wohlwend, D.,Hugle, M.,Schmidtkunz, K.,Gerhardt, S.,Schule, R.,Jung, M.,Einsle, O.,Gunther, S. 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52:14055-14059, 2013 Cited by PubMed: 24272870DOI: 10.1002/anie.201307652 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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