4LU3
The crystal structure of the human carbonic anhydrase XIV
Summary for 4LU3
Entry DOI | 10.2210/pdb4lu3/pdb |
Descriptor | Carbonic anhydrase 14, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total) |
Functional Keywords | zinc binding, glycoprotein, membrane, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 33077.71 |
Authors | Alterio, V.,De Simone, G.,Monti, S.M. (deposition date: 2013-07-24, release date: 2014-01-01, Last modification date: 2023-09-20) |
Primary citation | Alterio, V.,Pan, P.,Parkkila, S.,Buonanno, M.,Supuran, C.T.,Monti, S.M.,De Simone, G. The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitors. Biopolymers, 101:769-778, 2014 Cited by PubMed: 24374484DOI: 10.1002/bip.22456 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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