4LOR
C1s CUB1-EGF-CUB2 in complex with a collagen-like peptide from C1q
Summary for 4LOR
Entry DOI | 10.2210/pdb4lor/pdb |
Descriptor | Complement C1s subcomponent heavy chain, collagen-like peptide from C1q, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | cub domain, egf-like domain, protein collagen complex, c1 complex, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 38942.01 |
Authors | Wallis, R.,Venkatraman Girija, U.,Moody, P.C.E.,Marshall, J.E. (deposition date: 2013-07-13, release date: 2013-08-07, Last modification date: 2020-07-29) |
Primary citation | Venkatraman Girija, U.,Gingras, A.R.,Marshall, J.E.,Panchal, R.,Sheikh, M.A.,Gal, P.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.,Wallis, R. Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation. Proc.Natl.Acad.Sci.USA, 110:13916-13920, 2013 Cited by PubMed: 23922389DOI: 10.1073/pnas.1311113110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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