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4LJQ

Crystal structure of the catalytic core of E3 ligase HOIP

Summary for 4LJQ
Entry DOI10.2210/pdb4ljq/pdb
Related4LJO 4LJP
DescriptorE3 ubiquitin-protein ligase RNF31, ZINC ION (3 entities in total)
Functional Keywordsrnf31, zibra, ring domain, zinc finger, ibr domain, rbr ligase, e3 ligase, ligase, ubiquitin, hoil-1, sharpin
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity): Q96EP0
Total number of polymer chains4
Total formula weight102138.75
Authors
Stieglitz, B.,Rana, R.R.,Koliopoulos, M.G.,Morris-Davies, A.C.,Christodoulou, E.,Howell, S.,Brown, N.R.,Rittinger, K. (deposition date: 2013-07-05, release date: 2013-10-16, Last modification date: 2013-12-18)
Primary citationStieglitz, B.,Rana, R.R.,Koliopoulos, M.G.,Morris-Davies, A.C.,Schaeffer, V.,Christodoulou, E.,Howell, S.,Brown, N.R.,Dikic, I.,Rittinger, K.
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503:422-426, 2013
Cited by
PubMed: 24141947
DOI: 10.1038/nature12638
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

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