4LJQ
Crystal structure of the catalytic core of E3 ligase HOIP
Summary for 4LJQ
Entry DOI | 10.2210/pdb4ljq/pdb |
Related | 4LJO 4LJP |
Descriptor | E3 ubiquitin-protein ligase RNF31, ZINC ION (3 entities in total) |
Functional Keywords | rnf31, zibra, ring domain, zinc finger, ibr domain, rbr ligase, e3 ligase, ligase, ubiquitin, hoil-1, sharpin |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): Q96EP0 |
Total number of polymer chains | 4 |
Total formula weight | 102138.75 |
Authors | Stieglitz, B.,Rana, R.R.,Koliopoulos, M.G.,Morris-Davies, A.C.,Christodoulou, E.,Howell, S.,Brown, N.R.,Rittinger, K. (deposition date: 2013-07-05, release date: 2013-10-16, Last modification date: 2013-12-18) |
Primary citation | Stieglitz, B.,Rana, R.R.,Koliopoulos, M.G.,Morris-Davies, A.C.,Schaeffer, V.,Christodoulou, E.,Howell, S.,Brown, N.R.,Dikic, I.,Rittinger, K. Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature, 503:422-426, 2013 Cited by PubMed: 24141947DOI: 10.1038/nature12638 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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