4LHI
Crystal structure of human carbonic anhydrase isozyme II with 5-(phenylsulfonyl)thiophene-2-sulfonamide
Summary for 4LHI
Entry DOI | 10.2210/pdb4lhi/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29814.12 |
Authors | Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2013-07-01, release date: 2014-07-02, Last modification date: 2023-11-08) |
Primary citation | Smirnov, A.,Manakova, E.,Grazulis, S.,Matulis, D. Crystal structure of human carbonic anhydrase isozyme II with 5-(phenylsulfonyl)thiophene-2-sulfonamide To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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