4LBU
tRNA guanine transglycosylase (TGT) in complex with Furanoside-Based lin-Benzoguanine 2
Summary for 4LBU
Entry DOI | 10.2210/pdb4lbu/pdb |
Related | 1PUD 2Z7K 3EOS 4KWO 4LEQ |
Descriptor | Queuine tRNA-ribosyltransferase, methyl 6-[6-amino-2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-4-yl]-5,6-dideoxy-2-O-methyl-beta-D-ribo-hexofuranoside, ZINC ION, ... (6 entities in total) |
Functional Keywords | tim barrel, glycosyltransferase, zinc-binding, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zymomonas Mobilis subsp. mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43851.39 |
Authors | Ehrmann, F.R.,Heine, A.,Klebe, G. (deposition date: 2013-06-21, release date: 2014-12-24, Last modification date: 2023-09-20) |
Primary citation | Barandun, L.J.,Ehrmann, F.R.,Zimmerli, D.,Immekus, F.,Giroud, M.,Grunenfelder, C.,Schweizer, W.B.,Bernet, B.,Betz, M.,Heine, A.,Klebe, G.,Diederich, F. Replacement of Water Molecules in a Phosphate Binding Site by Furanoside-Appended lin-Benzoguanine Ligands of tRNA-Guanine Transglycosylase (TGT). Chemistry, 21:126-135, 2015 Cited by PubMed: 25483606DOI: 10.1002/chem.201405764 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.17 Å) |
Structure validation
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