4L4V

Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH

Summary for 4L4V

• Entry DOI: 10.2210/pdb4l4v/pdb
• Related: 4GUP 4L4T
• Descriptor: Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ... (7 entities in total)
• Functional Keywords: mhc class i-related protein, mait tcr, immune system, vitamin b metabolites, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane; Single-pass membrane protein; Extracellular side. Isoform 4: Secreted: Q95460; Secreted: P61769
• Total number of polymer chains: 8
• Total formula weight: 188245.77

Authors

Patel, O.,Kjer-Nielsen, L.,Le Nours, J.,Eckle, S.B.G.,Birkinshaw, R.W.,Beddoe, T.,Corbett, A.J.,Liu, L.,Miles, J.J.,Meehan, B.,Reantragoon, R.,Sandoval-Romero, M.L.,Sullivan, L.C.,Brooks, A.G.,Chen, Z.,Fairlie, D.P.,McCluskey, J.,Rossjohn, J. (deposition date: 2013-06-09, release date: 2013-07-17, Last modification date: 2023-09-20)

• Primary citation: Patel, O.,Kjer-Nielsen, L.,Le Nours, J.,Eckle, S.B.,Birkinshaw, R.,Beddoe, T.,Corbett, A.J.,Liu, L.,Miles, J.J.,Meehan, B.,Reantragoon, R.,Sandoval-Romero, M.L.,Sullivan, L.C.,Brooks, A.G.,Chen, Z.,Fairlie, D.P.,McCluskey, J.,Rossjohn, J.; Recognition of vitamin B metabolites by mucosal-associated invariant T cells.; Nat Commun, 4:2142-2142, 2013; PubMed: 23846752; DOI: 10.1038/ncomms3142

Experimental method

X-RAY DIFFRACTION (1.9 Å)