4KWW
The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid
Summary for 4KWW
Entry DOI | 10.2210/pdb4kww/pdb |
Related | 4KWV |
Descriptor | Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID (3 entities in total) |
Functional Keywords | nad, metabolism, type ii phosphoribosyltransferase, quinolinic acid, prpp, brain, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 188039.74 |
Authors | Malik, S.S.,Dimeka, P.N.,Ncube, Z.,Toth, E.A. (deposition date: 2013-05-24, release date: 2013-10-02, Last modification date: 2023-09-20) |
Primary citation | Malik, S.S.,Patterson, D.N.,Ncube, Z.,Toth, E.A. The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins, 82:405-414, 2014 Cited by PubMed: 24038671DOI: 10.1002/prot.24406 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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