4KWW
The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | polymer | 301 | 31173.8 | 6 | UniProt (Q15274) Pfam (PF02749) Pfam (PF01729) In PDB | Homo sapiens (human) | Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase |
| 2 | A, B, C, D, E... | PHTHALIC ACID | non-polymer | 166.1 | 6 | Chemie (PHT) | |||
| 3 | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 297 (UniProt: Q15274)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 187043.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 996.8 | |
| All* | Total formula weight | 188039.7 |
