4KW6

Crystal structure of Peroxiredoxin-1 (C-terminal truncation mutant) from the human hookworm Ancylostoma ceylanicum bound to conoidin A

Summary for 4KW6

Entry DOI	10.2210/pdb4kw6/pdb
Related	4FH8
Descriptor	Peroxiredoxin-1, 2,3-bis(bromomethyl)quinoxaline 1,4-dioxide (3 entities in total)
Functional Keywords	2-cys peroxiredoxin, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Ancylostoma ceylanicum
Total number of polymer chains	5
Total formula weight	101851.93
Authors	Nguyen, J.B.,Modis, Y. (deposition date: 2013-05-23, release date: 2013-07-31, Last modification date: 2023-09-20)
Primary citation	Nguyen, J.B.,Pool, C.D.,Wong, C.Y.,Treger, R.S.,Williams, D.L.,Cappello, M.,Lea, W.A.,Simeonov, A.,Vermeire, J.J.,Modis, Y. Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A. Chem.Biol., 20:991-1001, 2013 Cited by PubMed: 23891152 DOI: 10.1016/j.chembiol.2013.06.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation