4KBB

Structure of Botulinum neurotoxin B binding domain in complex with both synaptotagmin II and GD1a

Summary for 4KBB

Entry DOI	10.2210/pdb4kbb/pdb
Descriptor	Botulinum neurotoxin type B, Synaptotagmin-2, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	toxin binding domain, synaptotagmin and ganglioside, signaling protein-toxin complex, signaling protein/toxin
Biological source	Clostridium botulinum More
Total number of polymer chains	4
Total formula weight	127619.50
Authors	Berntsson, R.P.A.,Peng, L.,Dong, M.,Stenmark, P. (deposition date: 2013-04-23, release date: 2013-07-03, Last modification date: 2024-02-28)
Primary citation	Berntsson, R.P.,Peng, L.,Dong, M.,Stenmark, P. Structure of dual receptor binding to botulinum neurotoxin B. Nat Commun, 4:2058-2058, 2013 Cited by PubMed: 23807078 DOI: 10.1038/ncomms3058 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation