4K7F

Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201

Summary for 4K7F

• Entry DOI: 10.2210/pdb4k7f/pdb
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Core protein, ... (4 entities in total)
• Functional Keywords: host-virus interaction, immune response, disease mutation, viral replication, ig-like domain, immune system, tcr, membrane glycoprotein, viral capsid protein
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• Total number of polymer chains: 6
• Total formula weight: 89595.67

Authors

Meng, S.D.,Zhang, Y.,Wu, Y.,Qi, J.X. (deposition date: 2013-04-17, release date: 2013-06-05, Last modification date: 2022-08-24)

• Primary citation: Zhang, Y.,Ren, Y.,Wu, Y.,Zhao, B.,Qiu, L.,Li, X.,Xu, D.,Liu, J.,Gao, G.F.,Meng, S.; The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication.; J.Virol., 87:8075-8084, 2013; PubMed: 23678186; DOI: 10.1128/JVI.00577-13

Experimental method

X-RAY DIFFRACTION (2 Å)