4JM2
Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab
Summary for 4JM2
Entry DOI | 10.2210/pdb4jm2/pdb |
Related | 4JM4 |
Descriptor | PGT 135 Heavy chain, TETRAETHYLENE GLYCOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total) |
Functional Keywords | immunoglobulin fold, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 158950.50 |
Authors | Kong, L.,Wilson, I.A. (deposition date: 2013-03-13, release date: 2013-05-29, Last modification date: 2020-07-29) |
Primary citation | Kong, L.,Lee, J.H.,Doores, K.J.,Murin, C.D.,Julien, J.P.,McBride, R.,Liu, Y.,Marozsan, A.,Cupo, A.,Klasse, P.J.,Hoffenberg, S.,Caulfield, M.,King, C.R.,Hua, Y.,Le, K.M.,Khayat, R.,Deller, M.C.,Clayton, T.,Tien, H.,Feizi, T.,Sanders, R.W.,Paulson, J.C.,Moore, J.P.,Stanfield, R.L.,Burton, D.R.,Ward, A.B.,Wilson, I.A. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat.Struct.Mol.Biol., 20:796-803, 2013 Cited by PubMed: 23708606DOI: 10.1038/nsmb.2594 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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