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4JFH

High Affinity alpha24-beta17 T Cell Receptor for A2 HLA-Melanoma peptide complex

Summary for 4JFH
Entry DOI10.2210/pdb4jfh/pdb
Related4JFD 4JFE 4JFF 4JFO 4JFP 4JFQ
Descriptoralpha24 TCR allele, beta17 TCR allele, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywordsimmunoglobulin, hla, tcr, melanoma, immune system, high affinity
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total formula weight50250.48
Authors
Rizkallah, P.J.,Cole, D.K.,Madura, F.,Sewell, A.K. (deposition date: 2013-02-28, release date: 2013-05-29, Last modification date: 2013-07-17)
Primary citationMadura, F.,Rizkallah, P.J.,Miles, K.M.,Holland, C.J.,Bulek, A.M.,Fuller, A.,Schauenburg, A.J.,Miles, J.J.,Liddy, N.,Sami, M.,Li, Y.,Hossain, M.,Baker, B.M.,Jakobsen, B.K.,Sewell, A.K.,Cole, D.K.
T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288:18766-18775, 2013
Cited by
PubMed: 23698002
DOI: 10.1074/jbc.M113.464560
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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