4JEH

Crystal Structure of Munc18a and Syntaxin1 lacking N-peptide complex

Summary for 4JEH

• Entry DOI: 10.2210/pdb4jeh/pdb
• Related: 4JEU
• Descriptor: Syntaxin-binding protein 1, Syntaxin-1A (3 entities in total)
• Functional Keywords: protein complex, membrane, phosphoprotein, protein transport, transport, neurotransmitter transport, transmembrane, endocytosis-exocytosis complex, endocytosis/exocytosis
• Biological source: Rattus norvegicus (rat); More
• Cellular location: Cytoplasm: P61765; Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein (By similarity): P32851
• Total number of polymer chains: 2
• Total formula weight: 97591.46

Authors

Colbert, K.N.,Hattendorf, D.A.,Weiss, T.M.,Burkhardt, P.,Fasshauer, D.,Weis, W.I. (deposition date: 2013-02-27, release date: 2013-07-17, Last modification date: 2023-09-20)

• Primary citation: Colbert, K.N.,Hattendorf, D.A.,Weiss, T.M.,Burkhardt, P.,Fasshauer, D.,Weis, W.I.; Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.; Proc.Natl.Acad.Sci.USA, 110:12637-12642, 2013; PubMed: 23858467; DOI: 10.1073/pnas.1303753110

Experimental method

X-RAY DIFFRACTION (2.5 Å)