4JDT

Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1

Summary for 4JDT

• Entry DOI: 10.2210/pdb4jdt/pdb
• Related: 4JDV
• Descriptor: gp120, Fab heavy chain, Fab light chain, ... (5 entities in total)
• Functional Keywords: ig fold, anti hiv, antibody, immune system complex, viral protein-immune system complex, viral protein/immune system
• Biological source: Human Immunodeficiency Virus 1; More
• Total number of polymer chains: 3
• Total formula weight: 88708.44

Authors

Scharf, L.,Diskin, R.,Bjorkman, P.J. (deposition date: 2013-02-25, release date: 2013-03-20, Last modification date: 2023-09-20)

• Primary citation: Scharf, L.,West, A.P.,Gao, H.,Lee, T.,Scheid, J.F.,Nussenzweig, M.C.,Bjorkman, P.J.,Diskin, R.; Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.; Proc.Natl.Acad.Sci.USA, 110:6049-6054, 2013; PubMed: 23524883; DOI: 10.1073/pnas.1303682110

Experimental method

X-RAY DIFFRACTION (3.26 Å)