4J5A

Human Cyclophilin D Complexed with an Inhibitor

Summary for 4J5A

• Entry DOI: 10.2210/pdb4j5a/pdb
• Related: 4J58 4J59 4J5B 4J5C 4J5D 4J5E
• Descriptor: Peptidyl-prolyl cis-trans isomerase F, mitochondrial, 1-(4-aminobenzyl)-3-{2-[(2R)-2-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-2-oxoethyl}urea, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion matrix: P30405
• Total number of polymer chains: 1
• Total formula weight: 18142.74

Authors

Gelin, M.,Colliandre, L.,Bessin, Y.,Guichou, J.F. (deposition date: 2013-02-08, release date: 2014-02-19, Last modification date: 2024-02-28)

• Primary citation: Colliandre, L.,Hamed-Belkacem, H.,Gelin, M.,Bessin, Y.,Douguet, D.,Bourguet, W.,Pawlotsky, J.M.,Guichou, J.F.; Rationnal Design of small-molecule inhibitors of human Cyclophilins and HCV replication.; to be published,

Experimental method

X-RAY DIFFRACTION (1.58 Å)