4J5A
Human Cyclophilin D Complexed with an Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 164 | 17652.1 | 1 | UniProt (P30405) Pfam (PF00160) | Homo sapiens (human) | PPIase F, Cyclophilin F, Rotamase F |
| 2 | B (X) | 1-(4-aminobenzyl)-3-{2-[(2R)-2-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-2-oxoethyl}urea | non-polymer | 412.5 | 1 | Chemie (67Z) | |||
| 3 | C (X) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D (X) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence modifications
X: 44 - 207 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Ile 175 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17652.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 490.6 | |
| All* | Total formula weight | 18142.7 |
