4IMA
The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP
Summary for 4IMA
Entry DOI | 10.2210/pdb4ima/pdb |
Descriptor | Pyruvate kinase, MANGANESE (II) ION, CITRATE ANION, ... (7 entities in total) |
Functional Keywords | human liver pyruvate kinase, oxidizable cysteine, phosphorylation, phosphoenolpyruvate, pep, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 236930.66 |
Authors | Zhang, B.,Holyoak, T.,Fenton, A.W.,Tang, Q.L.,Prasannan, C.B.,Deng, J.P. (deposition date: 2013-01-02, release date: 2013-01-23, Last modification date: 2023-09-20) |
Primary citation | Holyoak, T.,Zhang, B.,Deng, J.,Tang, Q.,Prasannan, C.B.,Fenton, A.W. Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase. Biochemistry, 52:466-476, 2013 Cited by PubMed: 23270483DOI: 10.1021/bi301341r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.954 Å) |
Structure validation
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