4IMA
The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Pyruvate kinase | polymer | 543 | 58566.2 | 4 | UniProt (O75758) Pfam (PF00224) Pfam (PF02887) UniProt (by SIFTS) (P30613) In PDB | Homo sapiens (human) | |
| 2 | A, B, C, D | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | A, B, C, D | CITRATE ANION | non-polymer | 189.1 | 4 | Chemie (FLC) | |||
| 4 | A, B, C, D | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) | |||
| 5 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | D | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 7 | water | water | 18.0 | 859 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 543 (UniProt: O75758)
| PDB | External Database | Details |
|---|---|---|
| Met 436 | Cys 492 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 234264.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2665.9 | |
| All* | Total formula weight | 236930.7 |
