4IMA
The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase | polymer | 543 | 58566.2 | 4 | UniProt (O75758) Pfam (PF00224) Pfam (PF02887) UniProt (by SIFTS) (P30613) | Homo sapiens (human) | |
| 2 | E, H, L, O (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) PubChem (27854) | |||
| 3 | F, I, M, P (A, B, C, D) | CITRATE ANION | non-polymer | 189.1 | 4 | Chemie (FLC) PubChem (31348) | |||
| 4 | G, J, N, Q (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) PubChem (16219368) PubChem (718) PubChem (24802138) PubChem (10267) PubChem (46937007) PubChem (172313) PubChem (440117) PubChem (89534552) PubChem (445557) PubChem (92209487) PubChem (92209485) PubChem (92209486) PubChem (124383956) PubChem (124540446) PubChem (5702629) PubChem (135053794) PubChem (123134048) PubChem (124202619) PubChem (124427861) PubChem (124524513) PubChem (124604817) PubChem (12800340) PubChem (130233858) PubChem (133126640) PubChem (135055131) PubChem (140434362) PubChem (146159004) PubChem (160510795) | |||
| 5 | K (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | R (D) | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 7 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 859 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 543 (UniProt: O75758)
| PDB | External Database | Details |
|---|---|---|
| Met 436 | Cys 492 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 234264.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2665.9 | |
| All* | Total formula weight | 236930.7 |
