4IGK
Structure of human BRCA1 BRCT in complex with ATRIP peptide
Summary for 4IGK
Entry DOI | 10.2210/pdb4igk/pdb |
Related | 4IFI |
Descriptor | Breast cancer type 1 susceptibility protein, ATRIP peptide, GLYCEROL, ... (4 entities in total) |
Functional Keywords | cell cycle, disease mutation, dna damage, dna repair, fatty acid biosynthesis, ligase, lipid synthesis, metal-binding, nucleus, phosphoprotein, tumor suppressor, ubl conjugation pathway, zinc-finger, brct domain, dna damage response, phospho peptide interactions, dna-binding, phospho peptide binding, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus. Isoform 3: Cytoplasm. Isoform 5: Cytoplasm: P38398 Nucleus: Q8WXE1 |
Total number of polymer chains | 4 |
Total formula weight | 51008.37 |
Authors | Liu, X.,Ladias, J.A.A. (deposition date: 2012-12-17, release date: 2013-10-30, Last modification date: 2023-09-20) |
Primary citation | Liu, X.,Ladias, J.A. Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1. Biochemistry, 52:7618-7627, 2013 Cited by PubMed: 24073851DOI: 10.1021/bi400714v PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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