4IFI

Structure of human BRCA1 BRCT in complex with BAAT peptide

Summary for 4IFI

• Entry DOI: 10.2210/pdb4ifi/pdb
• Related: 4IGK
• Descriptor: Breast cancer type 1 susceptibility protein, BAAT peptide, ACETATE ION, ... (4 entities in total)
• Functional Keywords: cell cycle, disease mutation, dna damage, dna repair, fatty acid biosynthesis, ligase, lipid synthesis, metal-binding, nucleus, phosphoprotein, tumor suppressor, ubl conjugation pathway, zinc-finger, brct domain, dna damage response, phospho peptide interactions, dna-binding, phospho peptide binding, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus. Isoform 3: Cytoplasm. Isoform 5: Cytoplasm: P38398; Nucleus: Q6PJG6
• Total number of polymer chains: 2
• Total formula weight: 25363.04

Authors

Liu, X.,Ladias, J.A.A. (deposition date: 2012-12-14, release date: 2013-10-30, Last modification date: 2023-09-20)

• Primary citation: Liu, X.,Ladias, J.A.; Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1.; Biochemistry, 52:7618-7627, 2013; PubMed: 24073851; DOI: 10.1021/bi400714v

Experimental method

X-RAY DIFFRACTION (2.2 Å)