4I43
Crystal structure of Prp8:Aar2 complex
Summary for 4I43
Entry DOI | 10.2210/pdb4i43/pdb |
Related | 3ZEF |
Descriptor | A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 (3 entities in total) |
Functional Keywords | spliceosome, u5 snrnp, prp8, reverse transcriptase, aar2, endonuclease, rnase h, jab1/mpn, pre-mrna splicing, splicing |
Biological source | Saccharomyces cerevisiae (yeast) More |
Cellular location | Cytoplasm: P32357 Nucleus : P33334 |
Total number of polymer chains | 2 |
Total formula weight | 225184.79 |
Authors | Galej, W.P.,Oubridge, C.,Newman, A.J.,Nagai, K. (deposition date: 2012-11-27, release date: 2013-01-23, Last modification date: 2023-09-20) |
Primary citation | Galej, W.P.,Oubridge, C.,Newman, A.J.,Nagai, K. Crystal structure of Prp8 reveals active site cavity of the spliceosome. Nature, 493:638-643, 2013 Cited by PubMed: 23354046DOI: 10.1038/nature11843 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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