4HZZ
Crystal structure of influenza neuraminidase N3-H274Y complexed with oseltamivir
Summary for 4HZZ
Entry DOI | 10.2210/pdb4hzz/pdb |
Related | 3CL0 4HZV 4HZW 4HZX 4HZY 4I00 |
Descriptor | Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | neuraminidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Influenza A virus |
Total number of polymer chains | 1 |
Total formula weight | 44711.13 |
Authors | Li, Q.,Qi, J.,Vavricka, C.J.,Gao, G.F. (deposition date: 2012-11-16, release date: 2013-11-06, Last modification date: 2023-11-08) |
Primary citation | Li, Q.,Qi, J.,Wu, Y.,Kiyota, H.,Tanaka, K.,Suhara, Y.,Ohrui, H.,Suzuki, Y.,Vavricka, C.J.,Gao, G.F. Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance. J.Virol., 87:10016-10024, 2013 Cited by PubMed: 23824808DOI: 10.1128/JVI.01129-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.601 Å) |
Structure validation
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