4HZZ
Crystal structure of influenza neuraminidase N3-H274Y complexed with oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neuraminidase | polymer | 387 | 43205.5 | 1 | UniProt (A9YN63) | Influenza A virus | |
| 2 | B, C (B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 3 | D, E (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 4 | F (A) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 1 | Chemie (G39) PubChem (40640967) PubChem (40640969) PubChem (40640971) PubChem (44345914) PubChem (40640973) PubChem (449381) PubChem (58753598) PubChem (4631786) PubChem (71038155) PubChem (71065667) PubChem (95162772) PubChem (121452907) PubChem (124637832) PubChem (129886749) PubChem (134694948) PubChem (137378365) | |||
| 5 | G (A) | water | water | 18.0 | 490 | Chemie (HOH) |
Sequence modifications
A: 83 - 469 (UniProt: A9YN63)
| PDB | External Database | Details |
|---|---|---|
| Tyr 274 | His 276 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43205.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 364.5 | |
| All* | Total formula weight | 44711.1 |
