4HLZ

Crystal Structure of Fab C179 in Complex with a H2N2 influenza virus hemagglutinin

Summary for 4HLZ

Entry DOI	10.2210/pdb4hlz/pdb
Descriptor	Hemagglutinin HA1, 1,2-ETHANEDIOL, Hemagglutinin HA2, ... (10 entities in total)
Functional Keywords	neutralizing antibodies, antibody affinity, antigens, epitopes, glycosylation, hemagglutinin glycoproteins, immunoglobulin fab fragments, h2n2 subtype, influenza vaccines, avian flu, envelope protein, viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus More
Total number of polymer chains	12
Total formula weight	319542.85
Authors	Dreyfus, C.,Wilson, I.A. (deposition date: 2012-10-17, release date: 2013-04-17, Last modification date: 2020-07-29)
Primary citation	Dreyfus, C.,Ekiert, D.C.,Wilson, I.A. Structure of a classical broadly neutralizing stem antibody in complex with a pandemic h2 influenza virus hemagglutinin. J.Virol., 87:7149-7154, 2013 Cited by PubMed: 23552413 DOI: 10.1128/JVI.02975-12 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation