4HLZ

Crystal Structure of Fab C179 in Complex with a H2N2 influenza virus hemagglutinin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Hemagglutinin HA1	polymer	327	36504.2	3	UniProt (C7S226) Pfam (PF00509)	Influenza A virus
2	B, D, F (B, D, F)	Hemagglutinin HA2	polymer	174	20139.3	3	UniProt (C7S226) Pfam (PF00509)	Influenza A virus
3	G, I, K (G, I, K)	Fab C179 heavy chain	polymer	229	24853.8	3		Mus musculus
4	H, J, L (H, J, L)	Fab C179 light chain	polymer	214	23479.9	3		Mus musculus
5	M, P (M, P)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
6	N (N)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
7	O, Q (O, Q)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
8	R, S, U, W, Z (A, B, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
9	AA, BA, DA, T, V... (H, J, L, B, D...)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
10	CA (J)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)

Sequence modifications

A, C, E: 10 - 329 (UniProt: C7S226)

PDB	External Database	Details
Pro 9	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	314931.7
Branched	Number of molecules	5
	Total formula weight	2770.6
Non-Polymers*	Number of molecules	13
	Total formula weight	1840.5
All*	Total formula weight	319542.9

*Water molecules are not included.